Nature Neuroscience - New Cover

Somatostatin and affective state discrimination

Scheggia, Managò and colleagues describe a specific subpopulation of somatostatin-expressing cortical neurons that has a primary role in orchestrating the ability of mice to discriminate positive and negative affective states in their conspecifics. 

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CreamCafe

Venerdì della Cultura - 1 Marzo 2019

CONVERGENCE NEUROSCIENCE

08-12 October 2018

PHENOTYPING ANIMAL MODELS OF NEURODEVELOPMENTAL DISORDERS (NDDS)

Clinical and Preclinical Translational Research in Psychiatric Disorders

5-8 June 2018

Sopsi 2016 - Video

IIT con Telethon per la ricerca sulle malattie rare

Sono due i ricercatori di IIT che si sono aggiudicati il più recente finanziamento da parte di Telethon per condurre progetti sulle malattie rare, Francesco Papaleo a Genova e Alessandro Gozzi a Rovereto. Il finanziamento totale è di circa 450 mila euro, che i ricercatori utilizzeranno per migliorare la conoscenza dei meccanismi biologi legati alla sindrome di DiGeorge e delle sindromi da deficit primario di creatina. Le due sindromi ricadono nella definizione di malattie rare, poiché l’incidenza nella popolazione è inferiore alla soglia di 5 persone su 10000, definita a livello europeo.

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International Summer School of Neuroscience

10-14 July 2017

Schizofrenia e l'influenza dei geni

Leggi l'articolo completo qui

WIRED: Intervista a Francesco Papaleo

Leggi l'intervista su Wired

VIDEO: An Operant Intra-/Extra-dimensional Set-shift Task for Mice

Attentional set-shifting cognitive abnormalities are a core feature of many psychiatric diseases. Here, we present the development of a novel automatic system for the effective study of attentional set-shifting abilities, executive functions and other cognitive abilities in mice with high translational validity to human studies.

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Researchers Reverse Cognitive and Behavioral Deficits in New Mouse Model for Schizophrenia

Researchers have developed a new model for studying schizophrenia by genetically engineering mice that produce high levels of a human protein, NRG1-IV, in the brain. NRG1-IV, a protein that helps control the development and function of neurons, is overabundant in the brains of people with the schizophrenia who have a specific genetic variant in the NRG1 gene.

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Genetic Variations Reveal Which Patients Will Have Cognitive Benefits From Antipsychotic Medications

Antipsychotic medications are a cornerstone of treatment for schizophrenia and related disorders. They prevent hallucinations and delusions for most people, and for some, they also help reduce the cognitive impairments associated with these illnesses, such as problems with memory and attention. 

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